Nandrolone phenylpropionate dosage diseases caused by pathogens susceptible to the drug, including infections of the upper and lower respiratory tract, skin and soft tissue, urinary tract, joints, wounds, pelvic and abdominal cavity, biliary tract and gastrointestinal tract, gonorrhea, sepsis, osteomyelitis, peritonitis, meningitis.
Prevention of infectious complications during operations.
Hypersensitivity to cefuroxime and other beta-lactam antibiotics. Bleeding and gastrointestinal diseases in history, including ulcerative colitis. Precautions: Caution should be exercised when administering the drug: newborn, premature babies, weak and exhausted patients, patients with a severe impaired renal function, in colitis, with a reduced bleeding, gastric and duodenal ulcers, ulcerative colitis.
Pregnancy and lactation:
Use of the drug during pregnancy is possible only in cases where the potential benefit to the mother outweighs the potential risk to the fetus. If necessary, use during lactation should stop breastfeeding.
Dosage and administration:
The drug is administered intravenously nandrolone phenylpropionate dosage and intramuscularly. Intramuscular administration. To 750 mg 3 ml of water for injection and shaken gently until the slurry opaque.
For intravenous bolus of 750 mg drug is dissolved in at least 9 ml of water for injection. The solvent can be used as an isotonic sodium chloride solution or 5% glucose solution. Enter slowly for 3-5 minutes.
Adults / m or / appoint 0.75-1.5 g 3 times a day. If necessary, the interval between injections may be reduced to six hours; daily dose – 3-6 of
Children prescribed drug in a dose of 30-100 mg / kg / day in 3-4 administration. For most infections optimal daily dose of 60 mg / kg. Neonatal appoint 30-100 mg / kg / day in 2-3 administration. During the first weeks of life, half-life of serum cefuroxime neonatal blood can be 3-5 times higher than in adults.
In gonorrhea drug administered in a dose of 1.5 g in the form of one single injection or in two injections of 750 mg, administered in two buttocks .
When meningitis adults appoint 3 g / in every 8 hours. Babies infants and older administered 200-400 mg / kg / day I / 3-4 administration.
Upon reaching the optimal therapeutic effect dose can be reduced to 100 mg / kg / day intravenously. Newborns prescribed medication at a starting dose of 100 mg / kg / day intravenously.
Upon reaching the optimal therapeutic effect dose can be reduced to 50 mg / kg / day intravenously.
For the prevention of infections in the abdominal, pelvic or orthopedic operations a drug administered in / at an average dose of 1.5 . g simultaneously with the introduction of anesthesia
, if necessary may be additional administration / m at a dose of 750 mg after 8 and 16 hours.
in patients with impaired renal function at creatinine clearance 10-20 ml / min is recommended to inject the drug at 750 mg 2 times / day; when creatinine clearance less than 10 mL / min – 750 mg 1 time / day. Patients on dialysis at the end of each procedure introduced another 750 mg.
At constant peritoneal dialysis drug prescribed 750 mg 2 times / day.
On the part of the digestive tract: nausea, vomiting, diarrhea, cramping and abdominal pain; ulceration of the mucosa of the oral cavity; described cases of pseudomembranous colitis, candidiasis of the oral cavity.
From the hematopoietic system: anemia, eosinophilia, leucopenia, neutropenia.
With the genitourinary system: renal impairment, dysuria, itching in the perineum, vaginitis.
From the senses: hearing loss.
From the laboratory parameters: transient elevation of liver transaminases in plasma, increase in bilirubin, alkaline phosphatase.
Allergic reactions: skin rash, itching, hives, fever; very rarely – anaphylactic shock.
Local reactions:. pain, when administered nandrolone phenylpropionate dosage intravenously – thrombosis
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